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Maxillofacial Surgery

Issue


Regenerative medicine, tissue engineering,  bone substitutes, biomaterials,

stem cell research, clinical trials, animal trials, in-vitro trials


Personal Data


Sauerbier, Sebastian, MD, DDS


Department


University Medical Center Freiburg, Department of Maxillofacial Surgery,

Hard Tissue Research Laboratory, Cell Laboratory, Operating Unit


  • Internal Collaborations (University Medical Center Freiburg)

    Department of Experimental Surgery (Prof. Dr. J. Haberstroh)
    Section of clinical Neuropharmacology (Prof. Dr. T. Feuerstein)
    Department of Operative Dentistry and Periodontology (PD Dr. J. Schirrmeister, Dr. A. Al-Ahmad)
    MR Development and Application Center (MRDAC) (Dr. U. Fasol)
    Department of Neurosurgery (PD Dr. Vougioukas)

  • External Collaborations

    Harvard School of Engineering and Applied Sciences, Auguste Lab, Cambridge, USA (Dr. T Sachlos)
    German Cancer Research Center, Heidelberg (Dr. M. Palmowski)
    University Medical Center Mainz, Department of Maxillofacial Surgery (Prof. Dr. Dr. W. Wagner)
    University Medical Center Groningen, Netherlands, Department of Maxillofacial Surgery (Prof. Dr. G. Raghoebar)
    University of Trieste, Italy, Department of Oral Surgery (Prof. Dr. M. Maglione)
    University of Sao Paulo, Brazil, Faculdade de Odontologia de Ribeirão Preto (Dr. S. Xavier)

Know-How


    • Clinical Studies
    • In-vitro and In-vivo testing of biomaterials


Experience


    Since 2003 research fellow in the Department of Maxillofacial Surgery, University Medical Center Freiburg.

    Working in various clinical, animal and in-vitro trial projects.

    Since 2006 research-management of projects concerning regenerative approaches in oral- and maxillofacial surgery.



Publications


    1. Clinical Application of tissue engineered Transplants, Part I:  Mucosa, Sebastian Sauerbier, Ralf Gutwald, Margit Wiedmann-Al-Ahmad, Günter Lauer, Rainer Schmelzeisen, Clin Or Impl Res, 2006, Dec;17(6):625-32.

    2. Tissue Engineering, Sebastian Sauerbier, Rainer Schmelzeisen, Buchbeitrag in der 8. Auflage Herbst 2008, Zahn- Mund- und Kieferheilkunde, Schwenzer, Ehrenfeld Hrsg. , Thieme Verlag in press

    3. The Development of Plate Osteosynthesis for the Treatment of Mandibular Fractures – A literature Review, Sebastian Sauerbier, Ralf Schön, Jörg-Elard Otten, Rainer Schmelzeisen, Ralf Gutwald, Journal of Cranio- Maxillofacial Surgery, in press.

    4. Miniplate Osteosynthesis with four different Systems in Sheep, Ralf Gutwald, Ralf Schön, Kilian Kreutzer, Jens Kuschnierz, Berton Rahn, Rainer Schmelzeisen, Sebastian Sauerbier, submitted

    5. Bone Engineering: Allogenic and Alloplastic Bone Transplants vitalized by osteoblastlike Cells, Marc Hinze, Sebastian Sauerbier, Margit Wiedmann-Al-Ahmad, Ute Hübner, Rainer Schmelzeisen, International Poster Journal, Vol. 03/2007: 373


Current Projects


  • Clinical Investigation: “Sinus Floor Elevation with autogenous Stemcells and the Biomaterial Bio-Oss® for patients with alveolar atrophy”
  • Clinical Investigation: “Long Term Results of cultured autogenous Mucosa”
  • Animal Trial: “Collagen Constructs vitalized with osteoblastlike Cells in sheep” (AO-Research Grant)
  • In-Vitro Study: “Biocompatibility of different collagen Membranes”
  • In-Vitro Study: “Influence of GABA-Lactam analogues on osteoblastlike cells”
  • In-Vitro Study: “Influence of GABA-Lactam analogues on mesenchymal stem cells” (Camlog-Foundation Research Grant)
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